A Mediterranean diet rich in fiber, monounsaturated fats, and polyphenols improves immunotherapy response and progression-free survival in patients with advanced melanoma, according to a new study presented today at UEG Week 2022. related to improvement.
Experts believe diet plays an important role in the success of immunotherapy, and a growing body of research is investigating the outcome of various types of tumors, including gastrointestinal cancers.
Studies have found that diet plays an important role in the success of immunotherapy, and the study is being expanded to examine outcomes in different types of tumors, including gastrointestinal cancers.
A Mediterranean diet that includes mono- and polyunsaturated fats from olive oil, nuts, fish, polyphenols, and fiber from vegetables, fruits, and whole grains is used for immunotherapeutic drugs called immune checkpoint inhibitors (ICIs).
Highly successful in treating melanoma, ICIs work by blocking checkpoints in the immune system, allowing the body’s T cells to attack the cancer. increase.
A new multicenter study by British and Dutch researchers recorded food intake in 91 patients with advanced melanoma treated with ICI drugs and monitored progress with regular follow-up radiological examinations .
This diet was wasn’t only majorly associated with overall response rates, but also significantly associated with 12-month progression-free survival.
Her Laura Bolte, author of this study and PhD student, Rinse Weersma of the University Medical Center Groningen in the Netherlands commented:
Our study highlights the importance of nutritional assessment in cancer patients initiating ICI treatment and supports the role of nutritional strategies in improving patient outcomes and survival.
In addition to that red meat along with canned meat were present with a higher chance of immunity -related effects.
Improved treatment response High fiber diet, ketogenic diet, omega-3 fatty acids Clinical trials investigating the effects of supplementation are underway.
As ICI therapy expands to multiple tumor types, including colorectal cancer, these studies may unlock therapeutic benefits for a large number of cancer patient populations in the future,” added Laura Bolte.
The study also claims processed meat were associated with a high probability of immune-related adverse events.
The Mediterranean diet is based on the traditional foods people ate in Mediterranean countries such as France, Spain, Greece and Italy.
Researchers found that these people were very healthy and had a low risk of many chronic diseases.
There are no hard and fast rules or regulations regarding diet, but it generally encourages consumption of fruits, vegetables, whole grains, legumes, nuts, seeds and heart-healthy fats. Processed foods, added sugars, and refined grains should be limited.
Several studies have shown that the Mediterranean diet is beneficial for brain health and can even prevent age-related cognitive decline.
For example, a study of 512 people Adherence to a dietary regimen was found to improve memory and reduce several risk factors for Alzheimer’s disease.
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